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Activation-induced substrate engagement in ERK signaling

The extracellular signal-regulated kinase (ERK) pathway is an essential component of developmental signaling in metazoans. Previous models of pathway activation suggested that dissociation of activated dually phosphorylated ERK (dpERK) from MAPK/ERK kinase (MEK), a kinase that phosphorylates ERK, an...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Paul, Sayantanee, Yang, Liu, Mattingly, Henry, Goyal, Yogesh, Shvartsman, Stanislav Y., Veraksa, Alexey
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7183763/
https://ncbi.nlm.nih.gov/pubmed/31913744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E19-07-0355
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