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Sickle cell disease and malaria: decreased exposure and asplenia can modulate the risk from Plasmodium falciparum

BACKGROUND: Patients with sickle cell disease (SCD), an inherited haemoglobinopathy, have increased risk of malaria, at least in part due to impaired splenic function. Infection with Plasmodium falciparum in SCD patients can trigger painful vaso-occlusive crisis, increase the severity of anaemia, an...

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Detalhes bibliográficos
Publicado no:Malar J
Main Authors: Mwaiswelo, Richard O., Mawala, William, Iversen, Per O., de Montalembert, Mariane, Luzzatto, Lucio, Makani, Julie
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7183641/
https://ncbi.nlm.nih.gov/pubmed/32334583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-020-03212-w
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