Sickle cell disease and malaria: decreased exposure and asplenia can modulate the risk from Plasmodium falciparum

BACKGROUND: Patients with sickle cell disease (SCD), an inherited haemoglobinopathy, have increased risk of malaria, at least in part due to impaired splenic function. Infection with Plasmodium falciparum in SCD patients can trigger painful vaso-occlusive crisis, increase the severity of anaemia, an...

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Bibliografiske detaljer
Udgivet i:Malar J
Main Authors: Mwaiswelo, Richard O., Mawala, William, Iversen, Per O., de Montalembert, Mariane, Luzzatto, Lucio, Makani, Julie
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Case Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7183641/
https://ncbi.nlm.nih.gov/pubmed/32334583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-020-03212-w
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