Triple Drugs Co-Delivered by a Small Gemcitabine-Based Carrier for Pancreatic Cancer Immunochemotherapy

Poor tumor penetration and highly immunosuppressive tumor microenvironment are two major factors that limit the therapeutic efficacy for the treatment of pancreatic ductal adenocarcinoma (PDA). In this work, a redox-responsive gemcitabine (GEM)-conjugated polymer, PGEM, was employed as a tumor penet...

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Библиографические подробности
Опубликовано в: :Acta Biomater
Главные авторы: Sun, Jingjing, Wan, Zhuoya, Chen, Yichao, Xu, Jieni, Luo, Zhangyi, Parise, Robert A., Diao, Dingwei, Ren, Pengfei, Beumer, Jan H., Lu, Binfeng, Li, Song
Формат: Artigo
Язык:Inglês
Опубликовано: 2020
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7183357/
https://ncbi.nlm.nih.gov/pubmed/32004652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2020.01.039
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