Triple Drugs Co-Delivered by a Small Gemcitabine-Based Carrier for Pancreatic Cancer Immunochemotherapy

Poor tumor penetration and highly immunosuppressive tumor microenvironment are two major factors that limit the therapeutic efficacy for the treatment of pancreatic ductal adenocarcinoma (PDA). In this work, a redox-responsive gemcitabine (GEM)-conjugated polymer, PGEM, was employed as a tumor penet...

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Detalhes bibliográficos
Publicado no:Acta Biomater
Main Authors: Sun, Jingjing, Wan, Zhuoya, Chen, Yichao, Xu, Jieni, Luo, Zhangyi, Parise, Robert A., Diao, Dingwei, Ren, Pengfei, Beumer, Jan H., Lu, Binfeng, Li, Song
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7183357/
https://ncbi.nlm.nih.gov/pubmed/32004652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2020.01.039
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