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Modular repeat protein sculpting using rigid helical junctions
The ability to precisely design large proteins with diverse shapes would enable applications ranging from the design of protein binders that wrap around their target to the positioning of multiple functional sites in specified orientations. We describe a protein backbone design method for generating...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7183188/ https://ncbi.nlm.nih.gov/pubmed/32245816 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1908768117 |
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