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Modular repeat protein sculpting using rigid helical junctions
The ability to precisely design large proteins with diverse shapes would enable applications ranging from the design of protein binders that wrap around their target to the positioning of multiple functional sites in specified orientations. We describe a protein backbone design method for generating...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7183188/ https://ncbi.nlm.nih.gov/pubmed/32245816 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1908768117 |
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