Activity in grafted human iPS cell–derived cortical neurons integrated in stroke-injured rat brain regulates motor behavior

Stem cell transplantation can improve behavioral recovery after stroke in animal models but whether stem cell–derived neurons become functionally integrated into stroke-injured brain circuitry is poorly understood. Here we show that intracortically grafted human induced pluripotent stem (iPS) cell–d...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Palma-Tortosa, Sara, Tornero, Daniel, Grønning Hansen, Marita, Monni, Emanuela, Hajy, Mazin, Kartsivadze, Sopiko, Aktay, Sibel, Tsupykov, Oleg, Parmar, Malin, Deisseroth, Karl, Skibo, Galyna, Lindvall, Olle, Kokaia, Zaal
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2020
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7183146/
https://ncbi.nlm.nih.gov/pubmed/32253308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2000690117
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