Transcription factor programming of human ES cells generates functional neurons expressing both upper and deep layer cortical markers

Human neurodegenerative disorders affect specific types of cortical neurons. Efficient protocols for the generation of such neurons for cell replacement, disease modeling and drug screening are highly warranted. Current methods for the production of cortical neurons from human embryonic stem (ES) ce...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Miskinyte, Giedre, Grønning Hansen, Marita, Monni, Emanuela, Lam, Matti, Bengzon, Johan, Lindvall, Olle, Ahlenius, Henrik, Kokaia, Zaal
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6181302/
https://ncbi.nlm.nih.gov/pubmed/30307948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0204688
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