Angiotensin-converting-enzyme inhibitor prevents skeletal muscle fibrosis in myocardial infarction mice

BACKGROUND: Transforming growth factor beta (TGF-β)-Smad2/3 is the major signaling pathway of fibrosis, which is characterized by the excessive production and accumulation of extracellular matrix (ECM) components, including collagen. Although the ECM is an essential component of skeletal muscle, fib...

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Dades bibliogràfiques
Publicat a:Skelet Muscle
Autors principals: Kakutani, Naoya, Takada, Shingo, Nambu, Hideo, Matsumoto, Junichi, Furihata, Takaaki, Yokota, Takashi, Fukushima, Arata, Kinugawa, Shintaro
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7183133/
https://ncbi.nlm.nih.gov/pubmed/32334642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13395-020-00230-9
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