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Angiotensin-converting-enzyme inhibitor prevents skeletal muscle fibrosis in myocardial infarction mice

BACKGROUND: Transforming growth factor beta (TGF-β)-Smad2/3 is the major signaling pathway of fibrosis, which is characterized by the excessive production and accumulation of extracellular matrix (ECM) components, including collagen. Although the ECM is an essential component of skeletal muscle, fib...

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Detalhes bibliográficos
Publicado no:Skelet Muscle
Main Authors: Kakutani, Naoya, Takada, Shingo, Nambu, Hideo, Matsumoto, Junichi, Furihata, Takaaki, Yokota, Takashi, Fukushima, Arata, Kinugawa, Shintaro
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7183133/
https://ncbi.nlm.nih.gov/pubmed/32334642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13395-020-00230-9
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