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Interplay of Staphylococcal and Host Proteases Promotes Skin Barrier Disruption in Netherton Syndrome

Netherton syndrome (NS) is a monogenic skin disease resulting from loss of function of lymphoepithelial Kazal-type-related protease inhibitor (LEKTI-1). In this study we examine if bacteria residing on the skin are influenced by the loss of LEKTI-1 and if interaction between this human gene and resi...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Williams, Michael R., Cau, Laura, Wang, Yichen, Kaul, Drishti, Sanford, James A., Zaramela, Livia S., Khalil, Shadi, Butcher, Anna M., Zengler, Karsten, Horswill, Alexander R., Dupont, Christopher L., Hovnanian, Alain, Gallo, Richard L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7183042/
https://ncbi.nlm.nih.gov/pubmed/32130897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.02.021
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