Simple FISH-based evaluation of spermatic nuclear architecture shows an abnormal chromosomal organization in balanced chromosomal rearrangement carriers

INTRODUCTION: Interphasic DNA has a constant three-dimensional conformation, which is particularly striking for spermatic DNA, with distinct chromosomal territories and a constant chromosomal conformation. We hypothesized that this organization is fragile, and that an excess or a lack of chromosomal...

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Detalhes bibliográficos
Publicado no:J Assist Reprod Genet
Main Authors: Mebrek, Majda Lyna, Clède, Sylvain, de Chalus, Aliénor, Heide, Solveig, Ruoso, Léa, Rogers, Eli, Lédée, Nathalie, Prat-Ellenberg, Laura, Cassuto, Nino Guy, Siffroi, Jean-Pierre, Rouen, Alexandre
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2020
Assuntos:
Genetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7183033/
https://ncbi.nlm.nih.gov/pubmed/32193768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10815-020-01736-3
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