Simple FISH-based evaluation of spermatic nuclear architecture shows an abnormal chromosomal organization in balanced chromosomal rearrangement carriers

INTRODUCTION: Interphasic DNA has a constant three-dimensional conformation, which is particularly striking for spermatic DNA, with distinct chromosomal territories and a constant chromosomal conformation. We hypothesized that this organization is fragile, and that an excess or a lack of chromosomal...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Assist Reprod Genet
Prif Awduron: Mebrek, Majda Lyna, Clède, Sylvain, de Chalus, Aliénor, Heide, Solveig, Ruoso, Léa, Rogers, Eli, Lédée, Nathalie, Prat-Ellenberg, Laura, Cassuto, Nino Guy, Siffroi, Jean-Pierre, Rouen, Alexandre
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Springer US 2020
Pynciau:
Genetics
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7183033/
https://ncbi.nlm.nih.gov/pubmed/32193768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10815-020-01736-3
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