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Fluorescent substrates for haloalkane dehalogenases: Novel probes for mechanistic studies and protein labeling

Haloalkane dehalogenases are enzymes that catalyze the cleavage of carbon-halogen bonds in halogenated compounds. They serve as model enzymes for studying structure–function relationships of >100.000 members of the α/β-hydrolase superfamily. Detailed kinetic analysis of their reaction is crucial...

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Dettagli Bibliografici
Pubblicato in:Comput Struct Biotechnol J
Autori principali: Dockalova, Veronika, Sanchez-Carnerero, Esther M., Dunajova, Zuzana, Palao, Eduardo, Slanska, Michaela, Buryska, Tomas, Damborsky, Jiri, Klán, Petr, Prokop, Zbynek
Natura: Artigo
Lingua:Inglês
Pubblicazione: Research Network of Computational and Structural Biotechnology 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7182704/
https://ncbi.nlm.nih.gov/pubmed/32346465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2020.03.029
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