Loading...
STK25 suppresses Hippo signaling by regulating SAV1-STRIPAK antagonism
The MST-LATS kinase cascade is central to the Hippo pathway that controls tissue homeostasis, development, and organ size. The PP2A complex STRIPAK(SLMAP) blocks MST1/2 activation. The GCKIII family kinases associate with STRIPAK, but the functions of these phosphatase-associated kinases remain elus...
Saved in:
| Published in: | eLife |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
eLife Sciences Publications, Ltd
2020
|
| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7182433/ https://ncbi.nlm.nih.gov/pubmed/32292165 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.54863 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|