Preparation of Titanocene-Gold Compounds Based on Highly Active Gold(I)-N-Heterocyclic Carbene Anticancer Agents. Preliminary in vitro Studies in Renal and Prostate Cancer Cell lines.

Heterometallic titanocene-based compounds containing gold(I)-phosphane fragments have been extremely successful against renal cancer in vitro and in vivo. The exchange of phosphane by N-heterocyclic carbene ligands to improve or modulate their pharmacological profile afforded bimetallic complexes ef...

Full description

Saved in:
Bibliographic Details
Published in:ChemMedChem
Main Authors: Curado, Natalia, Giménez, Nora, Miachin, Kirill, Aliaga-Lavrijsen, Mélanie, Cornejo, Mike A., Jarzecki, Andrzej A., Contel, María
Format: Artigo
Language:Inglês
Published: 2019
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7181960/
https://ncbi.nlm.nih.gov/pubmed/30924298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201800796
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items