Preparation of Titanocene-Gold Compounds Based on Highly Active Gold(I)-N-Heterocyclic Carbene Anticancer Agents. Preliminary in vitro Studies in Renal and Prostate Cancer Cell lines.

Heterometallic titanocene-based compounds containing gold(I)-phosphane fragments have been extremely successful against renal cancer in vitro and in vivo. The exchange of phosphane by N-heterocyclic carbene ligands to improve or modulate their pharmacological profile afforded bimetallic complexes ef...

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Veröffentlicht in:ChemMedChem
Hauptverfasser: Curado, Natalia, Giménez, Nora, Miachin, Kirill, Aliaga-Lavrijsen, Mélanie, Cornejo, Mike A., Jarzecki, Andrzej A., Contel, María
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7181960/
https://ncbi.nlm.nih.gov/pubmed/30924298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201800796
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