CtBP determines ovarian cancer cell fate through repression of death receptors

C-terminal binding protein 2 (CtBP2) is elevated in epithelial ovarian cancer, especially in the aggressive and highly lethal subtype, high-grade serous ovarian cancer (HGSOC). However, whether HGSOC tumor progression is dependent on CtBP2 or its paralog CtBP1, is not well understood. Here we report...

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Bibliographic Details
Published in:Cell Death Dis
Main Authors: Ding, Boxiao, Yuan, Fang, Damle, Priyadarshan K., Litovchick, Larisa, Drapkin, Ronny, Grossman, Steven R.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7181866/
https://ncbi.nlm.nih.gov/pubmed/32332713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-2455-7
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