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The UPR sensor IRE1α and the adenovirus E3-19K glycoprotein sustain persistent and lytic infections
Persistent viruses cause chronic disease, and threaten the lives of immunosuppressed individuals. Here, we elucidate a mechanism supporting the persistence of human adenovirus (AdV), a virus that can kill immunosuppressed patients. Cell biological analyses, genetics and chemical interference demonst...
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| Udgivet i: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7181865/ https://ncbi.nlm.nih.gov/pubmed/32332742 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15844-2 |
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