Protective role of renal proximal tubular alpha-synuclein in the pathogenesis of kidney fibrosis

Kidney fibrosis is a highly deleterious process and a final manifestation of chronic kidney disease. Alpha-(α)-synuclein (SNCA) is an actin-binding neuronal protein with various functions within the brain; however, its role in other tissues is unknown. Here, we describe the expression of SNCA in ren...

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Vydáno v:Nat Commun
Hlavní autoři: Bozic, Milica, Caus, Maite, Rodrigues-Diez, Raul R., Pedraza, Neus, Ruiz-Ortega, Marta, Garí, Eloi, Gallel, Pilar, Panadés, Maria José, Martinez, Ana, Fernández, Elvira, Valdivielso, José Manuel
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7181766/
https://ncbi.nlm.nih.gov/pubmed/32327648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15732-9
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