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Glutamatergic Signaling Maintains the Epithelial Phenotype of Proximal Tubular Cells
Epithelial–mesenchymal transition (EMT) contributes to the progression of renal tubulointerstitial fibrosis. The N-methyl-d-aspartate receptor (NMDAR), which is present in proximal tubular epithelium, is a glutamate receptor that acts as a calcium channel. Activation of NMDAR induces actin rearrange...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society of Nephrology
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3103729/ https://ncbi.nlm.nih.gov/pubmed/21597037 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2010070701 |
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