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Deficiency in the autophagy modulator Dram1 exacerbates pyroptotic cell death of Mycobacteria-infected macrophages

DNA damage regulated autophagy modulator 1 (DRAM1) is a stress-inducible regulator of autophagy and cell death. DRAM1 has been implicated in cancer, myocardial infarction, and infectious diseases, but the molecular and cellular functions of this transmembrane protein remain poorly understood. Previo...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Zhang, Rui, Varela, Monica, Forn-Cuní, Gabriel, Torraca, Vincenzo, van der Vaart, Michiel, Meijer, Annemarie H.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7181687/
https://ncbi.nlm.nih.gov/pubmed/32332700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-2477-1
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