Enhanced succinic acid production by Mannheimia employing optimal malate dehydrogenase

Succinic acid (SA), a dicarboxylic acid of industrial importance, can be efficiently produced by metabolically engineered Mannheimia succiniciproducens. Malate dehydrogenase (MDH) is one of the key enzymes for SA production, but has not been well characterized. Here we report biochemical and structu...

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Udgivet i:Nat Commun
Main Authors: Ahn, Jung Ho, Seo, Hogyun, Park, Woojin, Seok, Jihye, Lee, Jong An, Kim, Won Jun, Kim, Gi Bae, Kim, Kyung-Jin, Lee, Sang Yup
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7181634/
https://ncbi.nlm.nih.gov/pubmed/32327663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15839-z
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