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Enhanced succinic acid production by Mannheimia employing optimal malate dehydrogenase

Succinic acid (SA), a dicarboxylic acid of industrial importance, can be efficiently produced by metabolically engineered Mannheimia succiniciproducens. Malate dehydrogenase (MDH) is one of the key enzymes for SA production, but has not been well characterized. Here we report biochemical and structu...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Ahn, Jung Ho, Seo, Hogyun, Park, Woojin, Seok, Jihye, Lee, Jong An, Kim, Won Jun, Kim, Gi Bae, Kim, Kyung-Jin, Lee, Sang Yup
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7181634/
https://ncbi.nlm.nih.gov/pubmed/32327663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15839-z
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