LGR5 marks targetable tumor-initiating cells in mouse liver cancer

Cancer stem cells (CSCs) or tumor-initiating cells (TICs) are thought to be the main drivers for disease progression and treatment resistance across various cancer types. Identifying and targeting these rare cancer cells, however, remains challenging with respect to therapeutic benefit. Here, we rep...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Cao, Wanlu, Li, Meng, Liu, Jiaye, Zhang, Shaoshi, Noordam, Lisanne, Verstegen, Monique M. A., Wang, Ling, Ma, Buyun, Li, Shan, Wang, Wenshi, Bolkestein, Michiel, Doukas, Michael, Chen, Kan, Ma, Zhongren, Bruno, Marco, Sprengers, Dave, Kwekkeboom, Jaap, J. W. van der Laan, Luc, Smits, Ron, Peppelenbosch, Maikel P., Pan, Qiuwei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7181628/
https://ncbi.nlm.nih.gov/pubmed/32327656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15846-0
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