Codon Usage and Splicing Jointly Influence mRNA Localization

In the human genome, most genes undergo splicing, and patterns of codon usage are splicing dependent: guanine and cytosine (GC) content is the highest within single-exon genes and within first exons of multi-exon genes. However, the effects of codon usage on gene expression are typically characteriz...

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Publicado no:Cell Syst
Main Authors: Mordstein, Christine, Savisaar, Rosina, Young, Robert S., Bazile, Jeanne, Talmane, Lana, Luft, Juliet, Liss, Michael, Taylor, Martin S., Hurst, Laurence D., Kudla, Grzegorz
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7181179/
https://ncbi.nlm.nih.gov/pubmed/32275854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2020.03.001
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