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Binding Kinetics of Ruthenium Pyrithione Chemotherapeutic Candidates to Human Serum Proteins Studied by HPLC-ICP-MS

The development of ruthenium-based complexes for cancer treatment requires a variety of pharmacological studies, one of them being a drug’s binding kinetics to serum proteins. In this work, speciation analysis was used to study kinetics of ruthenium-based drug candidates with human serum proteins. T...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Molecules
Hauptverfasser: Marković, Katarina, Milačič, Radmila, Marković, Stefan, Kladnik, Jerneja, Turel, Iztok, Ščančar, Janez
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7180866/
https://ncbi.nlm.nih.gov/pubmed/32225069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25071512
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