Synthesis, Docking Studies and Biological Activity of New Benzimidazole- Triazolothiadiazine Derivatives as Aromatase Inhibitor

In the last step of estrogen biosynthesis, aromatase enzyme catalyzes the conversion of androgens to estrogens. Aromatase inhibition is an important way to control estrogen-related diseases and estrogen levels. In this study, sixteen of benzimidazole-triazolothiadiazine derivatives have been synthes...

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Bibliographische Detailangaben
Veröffentlicht in:Molecules
Hauptverfasser: Acar Çevik, Ulviye, Kaya Çavuşoğlu, Betül, Sağlık, Begüm Nurpelin, Osmaniye, Derya, Levent, Serkan, Ilgın, Sinem, Özkay, Yusuf, Kaplancıklı, Zafer Asım
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7180718/
https://ncbi.nlm.nih.gov/pubmed/32252458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25071642
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