Human Serum Albumin Labelled with Sterically-Hindered Nitroxides as Potential MRI Contrast Agents

Four albumin-nitroxide conjugates were prepared and tested as metal-free organic radical contrast agents (ORCAs) for magnetic resonance imaging (MRI). Each human serum albumin (HSA) carrier bears multiple nitroxides conjugated via homocysteine thiolactones. These molecular conjugates retain importan...

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Bibliographic Details
Published in:Molecules
Main Authors: Dobrynin, Sergey, Kutseikin, Sergei, Morozov, Denis, Krumkacheva, Olesya, Spitsyna, Anna, Gatilov, Yurii, Silnikov, Vladimir, Angelovski, Goran, Bowman, Michael K., Kirilyuk, Igor, Chubarov, Alexey
Format: Artigo
Language:Inglês
Published: MDPI 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7180620/
https://ncbi.nlm.nih.gov/pubmed/32276437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25071709
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