Human Serum Albumin Labelled with Sterically-Hindered Nitroxides as Potential MRI Contrast Agents

Four albumin-nitroxide conjugates were prepared and tested as metal-free organic radical contrast agents (ORCAs) for magnetic resonance imaging (MRI). Each human serum albumin (HSA) carrier bears multiple nitroxides conjugated via homocysteine thiolactones. These molecular conjugates retain importan...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Dobrynin, Sergey, Kutseikin, Sergei, Morozov, Denis, Krumkacheva, Olesya, Spitsyna, Anna, Gatilov, Yurii, Silnikov, Vladimir, Angelovski, Goran, Bowman, Michael K., Kirilyuk, Igor, Chubarov, Alexey
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7180620/
https://ncbi.nlm.nih.gov/pubmed/32276437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25071709
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