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Comprehensive Evolutionary Analysis of Lamprey TNFR-Associated Factors (TRAFs) and Receptor-Interacting Protein Kinase (RIPKs) and Insights Into the Functional Characterization of TRAF3/6 and RIPK1

TNFR-associated factors (TRAFs) and receptor-interacting protein kinases (RIPKs) are important immunological linker molecules in mammals and play important roles in the TNFα, TLR and IFN signaling pathways. However, the evolutionary origins of these genes in vertebrates have not previously been desc...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Hou, Jianqiang, Pang, Yue, Li, Qingwei
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7179693/
https://ncbi.nlm.nih.gov/pubmed/32373123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00663
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