Dose Optimization of Cefpirome Based on Population Pharmacokinetics and Target Attainment during Extracorporeal Membrane Oxygenation

To obtain the optimal dosage regimen in patients receiving extracorporeal membrane oxygenation (ECMO), we developed a population pharmacokinetics model for cefpirome and performed pharmacodynamic analyses. This prospective study included 15 patients treated with cefpirome during ECMO. Blood samples...

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Dettagli Bibliografici
Pubblicato in:Antimicrob Agents Chemother
Autori principali: Kang, Soyoung, Jang, June Young, Hahn, Jongsung, Kim, Dasohm, Lee, Jun Yeong, Min, Kyoung Lok, Yang, Seungwon, Wi, Jin, Chang, Min Jung
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2020
Soggetti:
Clinical Therapeutics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7179593/
https://ncbi.nlm.nih.gov/pubmed/32122899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00249-20
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