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Population pharmacokinetics of intravenous sufentanil in critically ill patients supported with extracorporeal membrane oxygenation therapy

BACKGROUND: Sufentanil is commonly used for analgesia and sedation during extracorporeal membrane oxygenation (ECMO). Both ECMO and the pathophysiological changes derived from critical illness have significant effects on the pharmacokinetics (PK) of drugs, yet reports of ECMO and sufentanil PK are s...

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Detalhes bibliográficos
Publicado no:Crit Care
Main Authors: Hahn, Jongsung, Yang, Seungwon, Min, Kyoung Lok, Kim, Dasohm, Jin, Byung Hak, Park, Changhun, Park, Min Soo, Wi, Jin, Chang, Min Jung
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6615282/
https://ncbi.nlm.nih.gov/pubmed/31288863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13054-019-2508-4
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