Population pharmacokinetics of intravenous sufentanil in critically ill patients supported with extracorporeal membrane oxygenation therapy

BACKGROUND: Sufentanil is commonly used for analgesia and sedation during extracorporeal membrane oxygenation (ECMO). Both ECMO and the pathophysiological changes derived from critical illness have significant effects on the pharmacokinetics (PK) of drugs, yet reports of ECMO and sufentanil PK are s...

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Bibliographic Details
Published in:Crit Care
Main Authors: Hahn, Jongsung, Yang, Seungwon, Min, Kyoung Lok, Kim, Dasohm, Jin, Byung Hak, Park, Changhun, Park, Min Soo, Wi, Jin, Chang, Min Jung
Format: Artigo
Language:Inglês
Published: BioMed Central 2019
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6615282/
https://ncbi.nlm.nih.gov/pubmed/31288863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13054-019-2508-4
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