Considerations in the Selection of Renal Dosage Adjustments for Patients with Serious Infections and Lessons Learned from the Development of Ceftazidime-Avibactam

An extensive clinical development program (comprising two phase 2 and five phase 3 trials) has demonstrated the efficacy and safety of ceftazidime-avibactam in the treatment of adults with complicated intra-abdominal infection (cIAI), complicated urinary tract infection (cUTI), and hospital-acquired...

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Bibliographische Detailangaben
Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Li, Jianguo, Lovern, Mark, Riccobene, Todd, Carrothers, Timothy J., Newell, Paul, Das, Shampa, Talley, Angela K., Tawadrous, Margaret
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7179271/
https://ncbi.nlm.nih.gov/pubmed/32015049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02105-19
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