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A Supramolecular Approach to Structure-Based Design with A Focus on Synthons Hierarchy in Ornithine-Derived Ligands: Review, Synthesis, Experimental and in Silico Studies

The success of innovative drugs depends on an interdisciplinary and holistic approach to their design and development. The supramolecular architecture of living systems is controlled by non-covalent interactions to a very large extent. The latter are prone to extensive cooperation and like a virtuos...

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Bibliografiske detaljer
Udgivet i:Molecules
Main Authors: Bojarska, Joanna, Remko, Milan, Breza, Martin, Madura, Izabela D., Kaczmarek, Krzysztof, Zabrocki, Janusz, Wolf, Wojciech M.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7179192/
https://ncbi.nlm.nih.gov/pubmed/32138329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25051135
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