A Proline-Based Tectons and Supramolecular Synthons for Drug Design 2.0: A Case Study of ACEI

Proline is a unique, endogenous amino acid, prevalent in proteins and essential for living organisms. It is appreciated as a tecton for the rational design of new bio-active substances. Herein, we present a short overview of the subject. We analyzed 2366 proline-derived structures deposited in the C...

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Main Authors: Joanna Bojarska, Milan Remko, Martin Breza, Izabela Madura, Andrzej Fruziński, Wojciech M. Wolf
Formáid: Artigo
Teanga:Inglês
Foilsithe: MDPI AG 2020-10-01
Sraith:Pharmaceuticals
Ábhair:
proline
supramolecular synthon engineering
noncovalent interactions
drug design and discovery
ACEI
medicinal applications
Rochtain Ar Líne:https://www.mdpi.com/1424-8247/13/11/338
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