Targeting the 4-1BB costimulatory molecule through single chain antibodies promotes the human T-cell response

BACKGROUND: Adoptive T-cell therapy (ACT) using autologous tumor-reactive T lymphocytes has considerable potential for cancer immunotherapy. In ACT, T cells are isolated from cancer patients and then stimulated and expanded in vitro by cytokines and costimulatory molecules. 4-1BB is an important cos...

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Detalles Bibliográficos
Publicado en:Cell Mol Biol Lett
Main Authors: Bagheri, Salman, Safaie Qamsari, Elmira, Yousefi, Mehdi, Riazi-Rad, Farhad, Sharifzadeh, Zahra
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2020
Assuntos:
Research Letter
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7178758/
https://ncbi.nlm.nih.gov/pubmed/32336974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s11658-020-00219-8
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