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Antigen binding forces of individually addressed single-chain Fv antibody molecules

Antibody single-chain Fv fragment (scFv) molecules that are specific for fluorescein have been engineered with a C-terminal cysteine for a directed immobilization on a flat gold surface. Individual scFv molecules can be identified by atomic force microscopy. For selected molecules the antigen bindin...

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Detalhes bibliográficos
Main Authors: Ros, Robert, Schwesinger, Falk, Anselmetti, Dario, Kubon, Martina, Schäfer, Rolf, Plückthun, Andreas, Tiefenauer, Louis
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC22630/
https://ncbi.nlm.nih.gov/pubmed/9636161
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