Allelic-Specific Regulation of xCT Expression Increases Susceptibility to Tuberculosis by Modulating microRNA-mRNA Interactions

xCT forms part of the x(c)(−) cysteine-glutamate antiporter which inhibits antimicrobial inflammatory immune functions and thus increases susceptibility to tuberculosis (TB). However, the associations between xCT gene polymorphisms and susceptibility to TB, as well as whether these modulate xCT expr...

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Bibliografiske detaljer
Udgivet i:mSphere
Main Authors: Wang, Wenfei, Cai, Yi, Deng, Guofang, Yang, Qianting, Tang, Peijun, Wu, Meiying, Yu, Ziqi, Yang, Fan, Chen, Jianyong, Werz, Oliver, Chen, Xinchun
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7178550/
https://ncbi.nlm.nih.gov/pubmed/32321821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSphere.00263-20
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