Allelic-Specific Regulation of xCT Expression Increases Susceptibility to Tuberculosis by Modulating microRNA-mRNA Interactions

xCT forms part of the x(c)(−) cysteine-glutamate antiporter which inhibits antimicrobial inflammatory immune functions and thus increases susceptibility to tuberculosis (TB). However, the associations between xCT gene polymorphisms and susceptibility to TB, as well as whether these modulate xCT expr...

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Veröffentlicht in:mSphere
Hauptverfasser: Wang, Wenfei, Cai, Yi, Deng, Guofang, Yang, Qianting, Tang, Peijun, Wu, Meiying, Yu, Ziqi, Yang, Fan, Chen, Jianyong, Werz, Oliver, Chen, Xinchun
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2020
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7178550/
https://ncbi.nlm.nih.gov/pubmed/32321821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSphere.00263-20
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