B7-H3-Targeted CAR-T Cells Exhibit Potent Antitumor Effects on Hematologic and Solid Tumors

Recently, B7-H3 was frequently reported to be overexpressed in various cancer types and has been suggested to be a promising target for cancer immunotherapy. In the present study, we analyzed the mRNA expression of B7-H3 in The Cancer Genome Atlas (TCGA) database and validated its expression across...

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Publicat a:Mol Ther Oncolytics
Autors principals: Zhang, Zongliang, Jiang, Caiying, Liu, Zhiyong, Yang, Meijia, Tang, Xin, Wang, Yuelong, Zheng, Meijun, Huang, Jianhan, Zhong, Kunhong, Zhao, Shasha, Tang, Mei, Zhou, Tingyue, Yang, Hui, Guo, Gang, Zhou, Liangxue, Xu, Jianguo, Tong, Aiping
Format: Artigo
Idioma:Inglês
Publicat: American Society of Gene & Cell Therapy 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7178328/
https://ncbi.nlm.nih.gov/pubmed/32346608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omto.2020.03.019
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