Activation of PKG and Akt Is Required for Cardioprotection by Ramelteon-Induced Preconditioning and Is Located Upstream of mKCa-Channels

Ramelteon is a Melatonin 1 (MT1)—and Melatonin 2 (MT2)—receptor agonist conferring cardioprotection by pharmacologic preconditioning. While activation of mitochondrial calcium-sensitive potassium (mK(Ca))-channels is involved in this protective mechanism, the specific upstream signaling pathway of R...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Int J Mol Sci
Main Authors: Torregroza, Carolin, Jalajel, Osameh, Raupach, Annika, Feige, Katharina, Bunte, Sebastian, Heinen, André, Mathes, Alexander, Hollmann, Markus W., Huhn, Ragnar, Stroethoff, Martin
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7177737/
https://ncbi.nlm.nih.gov/pubmed/32276406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21072585
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki