Clinical Impact of Somatic Variants in Homologous Recombination Repair-Related Genes in Ovarian High-Grade Serous Carcinoma

PURPOSE: In this study, we investigated the frequencies of mutations in DNA damage repair genes including BRCA1, BRCA2, homologous recombination genes and TP53 gene in ovarian high-grade serous carcinoma, alongside those of germline and somatic BRCA mutations, with the aim of improving the identific...

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Veröffentlicht in:Cancer Res Treat
Hauptverfasser: Choi, Min Chul, Hwang, Sohyun, Kim, Sewha, Jung, Sang Geun, Park, Hyun, Joo, Won Duk, Song, Seung Hun, Lee, Chan, Kim, Tae-Heon, Kang, Haeyoun, An, Hee Jung
Format: Artigo
Sprache:Inglês
Veröffentlicht: Korean Cancer Association 2020
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7176973/
https://ncbi.nlm.nih.gov/pubmed/32019284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4143/crt.2019.207
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