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miR‐152‐5p suppresses glioma progression and tumorigenesis and potentiates temozolomide sensitivity by targeting FBXL7

A generally used chemotherapeutic drug for glioma, a frequently diagnosed brain tumour, is temozolomide (TMZ). Our study investigated the activity of FBXL7 and miR‐152‐5p in glioma. Levels of microRNA‐152‐5p (miR‐152‐5p) and the transcript and protein of FBXL7 were assessed by real‐time PCR and West...

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Bibliografiske detaljer
Udgivet i:J Cell Mol Med
Main Authors: Kong, Shiqi, Fang, Yanwei, Wang, Bingqian, Cao, Yingxiao, He, Runzhi, Zhao, Zongmao
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7176889/
https://ncbi.nlm.nih.gov/pubmed/32150671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.15114
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