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miR‐152‐5p suppresses glioma progression and tumorigenesis and potentiates temozolomide sensitivity by targeting FBXL7

A generally used chemotherapeutic drug for glioma, a frequently diagnosed brain tumour, is temozolomide (TMZ). Our study investigated the activity of FBXL7 and miR‐152‐5p in glioma. Levels of microRNA‐152‐5p (miR‐152‐5p) and the transcript and protein of FBXL7 were assessed by real‐time PCR and West...

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Библиографические подробности
Опубликовано в: :J Cell Mol Med
Главные авторы: Kong, Shiqi, Fang, Yanwei, Wang, Bingqian, Cao, Yingxiao, He, Runzhi, Zhao, Zongmao
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7176889/
https://ncbi.nlm.nih.gov/pubmed/32150671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.15114
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