Lgr5+ telocytes are a signaling source at the intestinal villus tip

The intestinal epithelium is a structured organ composed of crypts harboring Lgr5+ stem cells, and villi harboring differentiated cells. Spatial transcriptomics have demonstrated profound zonation of epithelial gene expression along the villus axis, but the mechanisms shaping this spatial variabilit...

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Vydáno v:Nat Commun
Hlavní autoři: Bahar Halpern, Keren, Massalha, Hassan, Zwick, Rachel K., Moor, Andreas E., Castillo-Azofeifa, David, Rozenberg, Milena, Farack, Lydia, Egozi, Adi, Miller, Dan R., Averbukh, Inna, Harnik, Yotam, Weinberg-Corem, Noa, de Sauvage, Frederic J., Amit, Ido, Klein, Ophir D., Shoshkes-Carmel, Michal, Itzkovitz, Shalev
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7176679/
https://ncbi.nlm.nih.gov/pubmed/32321913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15714-x
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