Possibility of cancer-stem-cell-targeted radioimmunotherapy for acute myelogenous leukemia using (211)At-CXCR4 monoclonal antibody

To explore stem-cell-targeted radioimmunotherapy with α-particles in acute myelogenous leukemia (AML), pharmacokinetics and dosimetry of the (211)At-labeled anti-C-X-C chemokine receptor type 4 monoclonal antibody ((211)At-CXCR4 mAb) were conducted using tumor xenografted mice. The biological half-l...

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Publicat a:Sci Rep
Autors principals: Oriuchi, Noboru, Aoki, Miho, Ukon, Naoyuki, Washiyama, Kohshin, Tan, Chengbo, Shimoyama, Saki, Nishijima, Ken-ichi, Takahashi, Kazuhiro, Ito, Hiroshi, Ikezoe, Takayuki, Zhao, Songji
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7176675/
https://ncbi.nlm.nih.gov/pubmed/32321944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-63557-9
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