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Store-operated Ca(2+) entry in primary murine lung fibroblasts is independent of classical transient receptor potential (TRPC) channels and contributes to cell migration

Stromal interaction molecules (STIM1, 2) are acting as sensors for Ca(2+) in intracellular stores and activate Orai channels at the plasma membrane for store-operated Ca(2+) entry (SOCE), while classical transient receptor potential (TRPC) channel mediate receptor-operated Ca(2+) entry (ROCE). Sever...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Bendiks, Larissa, Geiger, Fabienne, Gudermann, Thomas, Feske, Stefan, Dietrich, Alexander
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7176639/
https://ncbi.nlm.nih.gov/pubmed/32321939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-63677-2
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