Store-operated Ca(2+) entry in primary murine lung fibroblasts is independent of classical transient receptor potential (TRPC) channels and contributes to cell migration

Stromal interaction molecules (STIM1, 2) are acting as sensors for Ca(2+) in intracellular stores and activate Orai channels at the plasma membrane for store-operated Ca(2+) entry (SOCE), while classical transient receptor potential (TRPC) channel mediate receptor-operated Ca(2+) entry (ROCE). Sever...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Bendiks, Larissa, Geiger, Fabienne, Gudermann, Thomas, Feske, Stefan, Dietrich, Alexander
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7176639/
https://ncbi.nlm.nih.gov/pubmed/32321939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-63677-2
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